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Stem cell studies and applications which have a great resonance in the world are one of the subjects that excited both scientists and patients in recent years. Stem cell treatment methods are considered as the "biggest invention in medicine" in the current century.
Scientists continue to conduct intensive research on stem cells, while on the other hand they have included some of the cellular treatment methods in which stem cells are used. Cellular treatment methods are used in stem cells, especially orthopedics, plastic surgery and dermatology.
Extremely pleasing results were obtained from the autologous cartilage cell or stem cell applications obtained from the fat tissue of the person, especially in the cases of osteoarthritis, especially in the cartilages.
Breast reconstruction, non-healing chronic wounds, burn wounds and aesthetic / cosmetic stem cell therapies have become a routine practice. In the field of dermatology, especially in the treatment of skin rejuvenation and acne scars, the application of fibroblast cells obtained from the person gave positive results.
In advanced stages of Burger disease, which is a vascular occlusion problem, especially in smokers; finger, feet and legs can create the risk of cut. There may be serious pains that bind the patient to the bed. After stem cell transplantation, patients may be at risk of cutting their limbs and their quality of life may increase.
Scientists who found that the stem cell alone could produce enough specialized skin cells to cover the entire body, have come a long way in the treatment of skin burns in the light of this information.
In the UK and the USA, animal experiments were continued for spinal cord injury; In Germany, China and Russia, patients are transported their own cells. With stem cell applications of patients with spinal cord paralysis; It is observed that they can carry out functions such as moving their feet, holding their toilet and living a better quality life.
Stem cell applications in muscle wasting (Duchenn muscular distrophy) and children with Cerebral Palsy (CP) primarily stop the progression of the disease and show significant clinical improvement in some patients.
Diabetic foot wounds are one of the most important causes of long-term hospitalization of diabetes patients. The risk of amputation is 15-40 times higher in diabetic patients than in normal individuals. 8 percent of diabetic foot wounds seen in 25 percent of diabetic patients may result in foot or finger cuts. Since treatment options of diabetic foot patients are limited, amputation is often known as the last solution. However, the mortality rate in the first 5 years after diabetic foot discontinuation is between 39 and 68 percent.
Today, cellular treatment applications for wound healing is a new and effective method. In wound treatment, the treatment of diabetic foot wounds with regenerative cells applied to the surgical site has become possible. In addition to the effect of cellular therapy on diabetic wound healing, the fact that it can be applied in chronic or acute wounds also has a significant potential.
Stemal vascular fraction (SVF) is a stem cell-rich cell cocktail obtained by enzymatic decomposition of the fat from the abdomen by lipo-aspiration method. SVF applications rich in regenerating cells contribute to the healing of diabetic foot wounds by different mechanisms such as inhibition of cell death, collagen synthesis, growth factor release, neovascularization and cell proliferation.
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